Xevi Biarnés CV

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Dr. Xevi Biarnés

Associate Professor
Bioengineering Department, IQS.
Bioinformatics & molecular modeling.


Xevi Biarnés, Laboratory of Biochemistry
Bioengineering Department, Institut Químic de Sarrià, Universitat Ramon Llull
Via Augusta 390, 08017 Barcelona, Spain
Tel: +34-932672000, e-mail: xevi.biarnes@iqs.url.edu

A. Education

Institut Químic de Sarrià (IQS) Chemistry B.S. 2003
Univ Oberta de Catalunya (UOC) Bioinf. and Comp. Gen. P.G. 2008
Universitat de Barcelona (UB) Biotechnology Ph.D. 2007

B. Appointments

2017-present Associate Professor, Institut Químic de Sarrià, URL
2012-2017 Assistant Professor, Institut Químic de Sarrià, URL
2010-2011 Postdoctoral fellow, Institut Químic de Sarrià, URL
2008-2010 Postdoctoral fellow, International School for Advanced Studies, Italy
2003-2007 PhD fellow, Barcelona Science Park, UB.

C. Publications (full list Google Scholar Citations)

(i) Six recent relevant publications

L.Grifoll-Romero, M.A. Sainz-Polo, D. Albesa-Jové, M.E. Guerin, X. Biarnés, A. Planas. Structure-function relationships underlying the dual N-acetylmuramic and N-acetylglucosamine specificities of the peptidoglycan deacetylase PdaC from Bacillus subtilis. J. Biol. Chem. 294, 19066-80 (2019).

J. Romero-García, X. Biarnés, A. Planas. Essential mycoplasma glycolipid synthase adheres to the cell membrane by means of an amphipathic helix. Sci. Rep. 9, 1-11 (2019).

D. Albesa-Jové, J. Romero-García, E. Sancho-Vaello, F.X. Contreras, A. Rodrigo-Unzueta, N. Comino, A. Carreras-González, P. Arrasate, S. Urresti, X. Biarnés, A. Planas, M.E. Guerin. Structural snapshots and loop dynamics along the catalytic cycle of glycosyltransferase GpgS. Structure 25, 1034-1044. e3 (2017).

B. Bissaro, J. Durand, X. Biarnés, A. Planas, P. Monsan, M.J. O’Donohue, R. Fauré. Molecular Design of Non-Leloir Furanose-Transferring Enzymes from an α-l-Arabinofuranosidase: A Rationale for the Engineering of Evolved Transglycosylases. ACS Catal. 5, 4598-4611 (2015).

E. Andrés, D. Albesa-Jové, X. Biarnés, B. M. Moerschbacher, M. E. Guerin, A. Planas. Structural basis of chitin oligosaccharide deacetylation. Angew. Chem. Int. Ed. 53, 6882–6887 (2014).F. Baftizadeh, F. Pietrucci, X. Biarnés,

A. Laio. Nucleation process of a fibril precursor in the C-terminal segment of amyloid-β. Phys. Rev. Lett. 110, 168103 (2013).

(ii) Recent review publications

L. Grifoll, S. Pascual, H. Aragunde, X. Biarnés, A. Planas. Chitin deacetylases: structures, specificities, and biotech applications. Polymers 10, 352 (2018).

H. Aragunde, X.Biarnés, A.Planas. Substrate recognition and specificity of chitin deacetylases and related family 4 carbohydrate esterases. Int. J.Mol Sci. 19, 412 (2018).

D. Synergistic activities

1. Program coordinator: PhD Program in Bioengineering (2017-present). MS Program in Bioengineering (2012).

2. Member of Scientific societies: Societat Catalana de Química (2018 – present). Spanish Society of Biochemistry and Molecular Biology (2008-2018).

3. Awards: Illy – Best Young Oral Communication (International Carbohydrate Symposium 2012, Madrid). Best Poster award at 13th International Conference on Chitin and Chitosan 2015 (Münster). “Beatriu de Pinós” incoming post-doctoral fellowship at IQS (Generalitat de Catalunya, 2010). Start-cup Business Plan competition (Udine, 2008). “Beatriu de Pinós” outgoing post-doctoral fellowship at SISSA (Generalitat de Catalunya, 2008).

4. Organizer International Symposia, including:19th European Carbohydrate Symposium (EUROCARB2017), Barcelona 2017, Co-organizer. CPMD Meeting, Barcelona 2011, member of the local organizing committee.

5. Reviewer for leading journals including J.Chem.Inf.Model., ACS Omega, and research grants including ERC, PRACE.

6. Member of collaborative European projects: NANO3BIO (NanoBioEngineering of BioInspired BioPolymers, FP7, 2013-17); CHITOBIOENGINEERING (Metabolic and Enzyme Engineering for the Biotechnological Production of Partially Acetylated Chitosans, ERA-IB, 2011-14); and National projects (MINECO, Spain) 2005 and since 2010 (series of 3y projects)

7. Teaching: a) Degree in Chemistry, Degree in Chemical Engineering, Degree in Industrial Engineering, IQS, URL: Informatics (1st course); b) Degree in Biotechnology, IQS, URL: Informatics (1st course) and Bioinformatics (3rd course); c) Masters in Bioengineering, IQS, URL: Bioinformatics and Data Science (1st semester), Macromolecular Modelling (2nd semester).

E. Collaborators and other affiliations

(i) Collaborators (current): Dr. Alessandro Laio (SISSA, Trieste), Dr. Regis Faure (INSA, Toulouse), Dr. Carme Rovira (Univ. of Barcelona).

(ii) PhD thesis advisor and other graduate student programs
2 PhD thesis (2016-present). 12 Master thesis (2011-present). Host for 5 visitors (PhD students and postdocs from Europe and Israel). Jury member of PhD dissertations: 4 (national and international).