PhD Thesis

Tinkering with carbohydrate-active enzymes for novel specificities: Chitin deacetylases and Glycosidases.
PhD student: Sergi Pascual Torrent
PhD advisor: Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 1 March 20220.

Oligosacáridos de la leche materna, un reto para las leches de fórmula: Ingeniería de proteínas de la enzima lacto-N-biosidasa de Bifidobacterium bifidum para la síntesis de lacto-N-tetraosa.
PhD student: Mireaia Castejón-Vilatrsana
PhD advisor: Dr. Magda Faijes and Dr. Antoni Planas
University: Universitat Ramon Llull
University: IQS-Universitat Ramon Llull
Dissertation date: 14 Fbruary 2022.

Chitin and peptidoglycan deacetylases: discovery, characterization and engineering.
PhD student: Laia Grifoll Romero
PhD advisor: Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 29 September 2020. Thesis (tdx)

Design of a new biological platform for the production of glycoglycerolipids.
PhD student: Núria Orive Milla
PhD advisor: Dr. Magda Faijes and Dr. Antoni Planas
University: Universitat Ramon Llull
University: IQS-Universitat Ramon Llull
Dissertation date: 28 September 2020. Thesis (tdx)

Enginyeria de glicosintases derivades de quitinases GH18 per a la polimerització de quitooligosacàrids.
PhD student: Cristina Alsina Verdú
PhD advisor: Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 15 July 2019. Thesis (tdx)

Biotechnological production of galactosides of pharmaceutical interest: enzyme screening, engineering and application.
PhD student: Estela Castilla Ypas
PhD advisor: Dr. Antoni Planas and Dra. Teresa Pellicer
University: IQS-Universitat Ramon Llull
Dissertation date: 9 March 2018. Thesis (tdx)

Ingeniería enzimática de quitina desacetilasas y glicosintasas como biocatalizadores: diseño racional de la especificidad y evolución dirigida.
PhD student: Hugo Aragunde Pazos
PhD advisor: Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 29 September 2017. Thesis (tdx)

Biotechnological production of omega-3 polyunsaturated fatty acids by heterotrophic microalgae.
PhD student: Sergi Abad Sánchez
PhD advisor: Dr. Xavier Turon and Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 15 February 2017. Thesis (tdx)

Relación secuencia-estructura-función en glicosiltransferasas con plegamiento GTA: Una aproximación bioinformática.
PhD student: Javier Romero García
PhD advisor: Dr. Xevi Biarnés and Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 29 July 2016. Thesis (tdx)

Structural-functional analysis of lacto-N-biosidase from Bifidobacterium bifidum: a potential biocatalyst for the production of human milk oligosaccharides.
PhD student: Cristina Val Cid
PhD advisor: Dra. Magda Faijes and Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 8 July 2016. Thesis (tdx)

Glycosynthase technology for enzymatic synthesis of functionalized artificial polysaccharides as new biomaterials.
PhD student: Victoria Codera Pastor
PhD advisor: Dr. Antoni Planas and Dra. Magda Faijes
University: IQS-Universitat Ramon Llull
Dissertation date: 17 July 2015. Thesis (tdx)

Transthyretin familial amyloid polyneuropathy: novel therapeutics derived from drug repurposing and new insights in diagnosis through proteomic analysis of clinical samples.
PhD student: Marta Vilà Rico
PhD advisor: Dr. Antoni Planas and Dr. Francesc Canals
University: IQS-Universitat Ramon Llull
Dissertation date: 10 July 2015. Thesis (tdx)

Nous Desenvolupaments en Glicosintases. Enginyeria i Aplicacions.
PhD student: Xavier Francesc Pérez Javierre
PhD advisor: Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 7 July 2015. Thesis (tdx)

The DosRST two-component system of Mycobacterium tuberculosis: Characterizing the activation mechanism of DosR response regulator as a potential target for novel antimycobacterial drugs.
PhD student: Marta Marszalek
PhD advisor: Dra. Teresa Pellicer and Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 23 July 2014. Thesis (tdx)

Biosíntesi de glicolípids de membrana en Mycoplama genitalium: expressió, purificació i caracterització d’una glicosiltransferasa procesiva en la formació de glicosildiacilglicerols.
PhD student: Núria Martínez Mas
PhD advisor: Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 11 November 2011. Thesis (tdx)

Diseño, selección y producción de nuevos biolubricantes.
PhD student: Albert Garcia Colomer
PhD advisor: Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 3 November 2011. Thesis (tdx)

Enginyeria metabòlica d’Escherichia coli per a la producció de glicoglicerolípids.
PhD student: Neus Mora Buyé
PhD advisor: Dra. Magda Faijes and Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 17 October 2011. Thesis (tdx)

Biophysical studies of transthyretin stability, amyloidogenicity, and ligand binding in the search of therapeutic interventions for familial amyloid polyneuropathology.
PhD student: Joan Nieto Castro
PhD advisor: Dr. Antoni Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 1 September 2010

Engineering carbohydrate-active enzymes: specificity and activity remodeled.
PhD student: Trevor Addington
PhD advisor: Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 26 January 2009. Thesis (tdx)

Mecanisme enzimàtic de la 1,3-1,4-β-glucanasa de Bacillus licheniformis: estudis cinètics en estat estacionari i pre-estacionari.
PhD student: Mireia Abel Lluch
PhD advisor: Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 22 January 2009. Thesis (tdx)

Xyloglucan endo-transglycosylase (XET), a key enzyme in plant cell wall morphogenesis.
PhD student: Marc Saura
PhD advisor: Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 28 September 2007

Glicosiltransferasas en la biosíntesis de glicolípidos de membrana en Micoplasma genitalium.
PhD student: Eduardo Andrés
PhD advisor: Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 14 September 2007

Análisis mutacional del extremo C-terminal de la α-1,3-galactosiltransferasa bovina: estabilidad y catálisis.
PhD student: Javier Linares
PhD advisor: Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 12 September 2007

Análisis estructural-funcional de glicosiltransferasas.
PhD student: Ana Monegal
PhD advisor: Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 29 November 2004

Producció d’oligosacàrids funcionals per mitjà del rediseny enzimàtic: de glicosidases a glicosil transferases.
PhD student: Magda Faijes
PhD advisor: Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 24 July 2003

Estudio de la evolución bioquímica del proceso de compostaje de residuos ganaderos.
PhD student: Carlos Peláez
PhD advisor: Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 16 July 2003

Análisis y rediseño de la función y de la estabilidad de una 1,3-1,4-β-glucan 4-glunacohidrolasa por ingeniería de proteínas.
PhD student: Juan Cedano
PhD advisor: Dr. E. Querol and Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 11 Dicember 2001

Especificitat i mecanisme d’1,3-1,4-β-glucanases de Bacillus: mutagènesi, enzimologia i aplicació en síntesi enzimática.
PhD student: Josep Lluis Viladot
PhD advisor: Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 16 March 1999

1,3-1,4-β-glucanases bacterianes: anàlisi conformacional de lligands oligosacàrids i modelització. molecular d’un complex enzim-substrat.
PhD student: Teresa Dot
PhD advisor: Dr. A. Planas and Dr. J. Teixidó
University: IQS-Universitat Ramon Llull
Dissertation date: 12 June 1998

Anàlisi de l’estabilitat de la 1,3-1,4-β-D-glucà 4-glucahidrolasa de Bacillus licheniformis per enginyeria de proteïnes.
PhD student: Jaume Pons
PhD advisor: Dr. E. Querol and Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 1996

Catàlisi i especificitat de 1,3-1,4-β-D-glucà 4-glucahidrolases: enzimologia amb substrats i inhibidors sintètics.
PhD student: Carles Malet
PhD advisor: Dr. A. Planas and Dra. C. Brosa
University: IQS-Universitat Ramon Llull
Dissertation date: 30 May 1995

Anàlisi per mutagènesi dirigida i caracterització del centre actiu d’una 1,3-1,4-β-D-glucà 4-glucahidrolasa de Bacillus licheniformis.
PhD student: Miquel Juncosa
PhD advisor: Dr. E. Querol and Dr. A. Planas
University: IQS-Universitat Ramon Llull
Dissertation date: 1995